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Modulation of Morphine-induced Antinociception in Acute and Chronic Opioid Treatment by IbudilastLILIUS, Tuomas O; RAUHALA, Pekka V; KAMBUR, Oleg et al.Anesthesiology (Philadelphia). 2009, Vol 111, Num 6, pp 1356-1364, issn 0003-3022, 9 p.Article

Zl-n-91, a selective phosphodiesterase 4 inhibitor, suppresses inflammatory response in a COPD-like rat modelWANG, Ya-Juan; JIANG, Ya-Li; TANG, Hui-Fang et al.International immunopharmacology (Print). 2010, Vol 10, Num 2, pp 252-258, issn 1567-5769, 7 p.Article

Effects of the new benzimidazole derivative TAS-203, an orally active phosphodiesterase 4 inhibitor, on airway inflammation in rats and emetic responses in ferretsASAKA, Naomasa; KAKUO, Hiroyuki; OHMORI, Kouichi et al.Arzneimittel-Forschung. 2010, Vol 60, Num 9, pp 564-570, issn 0004-4172, 7 p.Article

The potential role of roflumilast : The new phosphodiesterase-4 inhibitorKARISH, Sarah B; GAGNON, James M.The Annals of pharmacotherapy. 2006, Vol 40, Num 6, pp 1096-1104, issn 1060-0280, 9 p.Article

Phosphodiesterase 4 Inhibitors in Inflammatory Bowel Disease: A Comprehensive Review : New Treatments of Inflammatory Bowel Disease (IBD) Including Ulcerative Colitis and Crohn's Disease and Irritable Bowel Syndrome (IBS)SALARI-SHARIF, Pooneh; ABDOLLAHI, Mohammad.Current pharmaceutical design (Print). 2010, Vol 16, Num 33, pp 3661-3667, issn 1381-6128, 7 p.Article

Cilomilast : Orally active selective phosphodiesterase- 4 inhibitor for treatment of chronic obstructive pulmonary diseaseMARTINA, Shaunta D; ISMAIL, Maha S; VESTA, Kimi S et al.The Annals of pharmacotherapy. 2006, Vol 40, Num 10, pp 1822-1828, issn 1060-0280, 7 p.Article

Roflumilast: A Novel Treatment for Chronic Obstructive Pulmonary DiseaseREID, Debra J; PHAM, Nga T.The Annals of pharmacotherapy. 2012, Vol 46, Num 4, pp 521-529, issn 1060-0280, 9 p.Article

Phosphodiesterase 4 inhibitors in chronic obstructive pulmonary disease : a new approach to oral treatmentCURRIE, Graeme P; BUTLER, Claire A; ANDERSON, Wendy J et al.British journal of clinical pharmacology. 2008, Vol 65, Num 6, pp 803-810, issn 0306-5251, 8 p.Article

Preparation of azaindolines and benzoyl substituted azaindolines: precursors of triazabenzo[cd]azulen-9-one PDE4 inhibitorsBADLAND, Matthew; DEVILLERS, Ingrid; WRIGGLESWORTH, Roger et al.Tetrahedron letters. 2011, Vol 52, Num 41, issn 0040-4039, 5202, 5292-5296 [6 p.]Article

Roflumilast, a phosphodiesterase 4 inhibitor, reduces airway hyperresponsiveness after allergen challengeLOUW, C; WILLIAMS, Z; VENTER, L et al.Respiration (Basel). 2007, Vol 74, Num 4, pp 411-417, issn 0025-7931, 7 p.Article

Apremilast: First Global ApprovalPOOLE, Raewyn M; BALLANTYNE, Anita D.Drugs (Basel). 2014, Vol 74, Num 7, pp 825-837, issn 0012-6667, 13 p.Article

Efficacy of apremilast in the treatment of moderate to severe psoriasis: a randomised controlled trialPAPP, Kim; CATHER, Jennifer C; ROSOPH, Les et al.Lancet (British edition). 2012, Vol 380, Num 9843, pp 738-746, issn 0140-6736, 9 p.Article

Rhumatisme psoriasique: Résultats de l'ustekinumab et de l'apremilastPACCOU, Julien.Rhumatos. 2012, Vol 9, Num 83, pp 447-450, issn 1771-0081, 4 p.Article

Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+ ) -2 -[4 -({[2 -(benzo[1,3 ]dioxol -5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and humanKALGUTKAR, Amit S; BO FENG; DUIGNAN, David B et al.Drug metabolism and disposition. 2007, Vol 35, Num 11, pp 2111-2118, issn 0090-9556, 8 p.Article

Theophylline inhibits the cough reflex through a novel mechanism of actionDUBUIS, Eric; WORTLEY, Michael A; GRACE, Megan S et al.Journal of allergy and clinical immunology. 2014, Vol 133, Num 6, pp 1588-1598, issn 0091-6749, 11 p.Article

Ibudilast in healthy volunteers : safety, tolerability and pharmacokinetics with single and multiple dosesROLAN, Paul; GIBBONS, Jacqueline A; LIN HE et al.British journal of clinical pharmacology. 2008, Vol 66, Num 6, pp 792-801, issn 0306-5251, 10 p.Article

Calorimetric determination of dissolution enthalpy with a novel flow-through methodLEHTO, Vesa-Pekka; TENHO, Mikko; HÄMÄLÄINEN, Olli-Pekka et al.Journal of pharmaceutical and biomedical analysis. 2010, Vol 53, Num 4, pp 821-825, issn 0731-7085, 5 p.Article

Accelerated Dissolution Testing for Controlled Release Microspheres Using the Flow-Through Dissolution ApparatusCOLLIER, Jarrod W; THAKARE, Mohan; GARNER, Solomon T et al.Pharmaceutical development and technology. 2009, Vol 14, Num 1, pp 9-17, issn 1083-7450, 9 p.Article

Differences in Characteristics of Pellets Prepared by Different Pelletization MethodsHÄRING, Adam; VETCHY, David; JANOVSKA, Lucie et al.Drug development and industrial pharmacy. 2008, Vol 34, Num 3, pp 289-296, issn 0363-9045, 8 p.Article

Shape optimization and characterization of polysaccharide beads prepared by ionotropic gelationSMRDEL, Polona; BOGATAJ, Marija; ZEGA, Anamarija et al.Journal of microencapsulation. 2008, Vol 25, Num 2, pp 90-105, issn 0265-2048, 16 p.Article

Aprémilast pour traiter l'arthrite psoriasique = Apremilast for psoriatic arthritisThe Medical letter on drugs and therapeutics (Edition française). 2014, Vol 36, Num 13, pp 53-54, issn 0253-8512, 2 p.Article

Intranasal Theophylline Treatment of Hyposmia and Hypogeusia: A Pilot StudyHENKIN, Robert I; SCHULTZ, Michael; MINNICK-POPPE, Laura et al.Archives of otolaryngology, head & neck surgery. 2012, Vol 138, Num 11, pp 1064-1070, issn 0886-4470, 7 p.Article

Phosphodiesterase 4 inhibitors enhance sexual pleasure-seeking activity in rodentsPEIXIONG YUAN; TRAGON, Tyson; GUITART, Xavier et al.Pharmacology, biochemistry and behavior. 2011, Vol 98, Num 3, pp 349-355, issn 0091-3057, 7 p.Article

Roller compaction of different pseudopolymorphic forms of Theophylline: Effect on compressibility and tablet propertiesHADZOVIC, Ervina; BETZ, Gabriele; HADZIDEDIC, Seherzada et al.International journal of pharmaceutics (Print). 2010, Vol 396, Num 1-2, pp 53-62, issn 0378-5173, 10 p.Article

Theophylline Improves Steroid Sensitivity in Acute Alcoholic HepatitisKENDRICK, Stuart F. W; HENDERSON, Elsbeth; PALMER, Jeremy et al.Hepatology (Baltimore, Md.). 2010, Vol 52, Num 1, pp 126-131, issn 0270-9139, 6 p.Article

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